Midamor (amiloride) is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. Midamor is used to treat fluid retention (edema) in people with congestive heart failure, liver cirrhosis, or kidney problems. Midamor is also used to treat high blood pressure (hypertension).

Midamor may also be used for purposes not listed in this medication guide.

Important Information

You should not use Midamor if you are allergic to amiloride, or if you have kidney disease, high levels of potassium in your blood, or a history of Addison's disease or adrenal gland tumor.

To make sure Midamor is safe for you, tell your doctor if you have:

  • kidney disease;
  • a history of kidney stones;
  • diabetes;
  • gout;
  • liver disease;
  • a history of liver disease or jaundice;
  • a history of Addison's disease or adrenal gland tumor;
  • high levels of potassium in your blood; or
  • if you are on a low-salt diet.

FDA pregnancy category C. Midamor may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether amiloride passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using Midamor.

How should I take Midamor?

Take Midamor exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not take this medicine in larger or smaller amounts or for longer than recommended.

Midamor is usually taken once daily, with or without food.

Your blood pressure will need to be checked often. You may need frequent blood tests to check your potassium level.

While using Midamor, you may need to take a potassium supplement or eat foods that are high in potassium (oranges, bananas, tomatoes, potatoes with the skin on).

Do not use salt substitutes or low-sodium milk products that contain potassium. These products could cause your potassium levels to get too high while you are taking Midamor.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your kidney or liver function may also need to be checked. Visit your doctor regularly.

If you need surgery, tell the surgeon ahead of time that you are using Midamor.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Midamor?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Midamor side effects

Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain, difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • little or no urinating;
  • swelling, rapid weight gain;
  • numbness, tingling, or burning pain in your hands or feet;
  • muscle weakness, cramps, or twitching;
  • a light-headed feeling, like you might pass out;
  • high potassium--nausea, slow or unusual heart rate, weakness, loss of movement; or
  • low potassium--confusion, irregular heartbeats, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling.

Common Midamor side effects may include:

  • mild nausea, vomiting;
  • blurred vision; or
  • mild diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Midamor dosing information

Usual Adult Dose for Edema:

  • Initial dose: 1 to 2 tablets per day

Usual Adult Dose for Hypertension:

  • Initial dose: 1 to 2 tablets per day

Missed Dose

  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.


  • Store at room temperature away from light and moisture. Do not store in the bathroom. Keep

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