Allopurinol

Allopurinol is a medication used to treat gout. It is a generic medication, which means it is available under many different brand names. Allopurinol is also available as a lower-cost generic.

Allopurinol works by reducing the amount of uric acid in the body. Uric acid is a substance that is produced when the body breaks down purines. Purines are found in many foods, such as organ meats, seafood, and legumes. When uric acid levels are too high, it can lead to gout.

Allopurinol is available as a tablet and an oral suspension. It is typically taken once daily. The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may start you at a low dose and gradually increase your dose.

Allopurinol is a prescription medication. It is not available over-the-counter (OTC).

Side Effects

Allopurinol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache
  • drowsiness
  • diarrhea
  • nausea
  • vomiting
  • rash

If you experience any of the following symptoms, call your doctor immediately:

  • fever
  • chills
  • sore throat
  • mouth sores
  • unusual bruising or bleeding
  • yellowing of the skin or eyes
  • dark urine
  • stomach pain

Interactions

Allopurinol may interact with other medications. Tell your doctor all prescription and over-the-counter medications and supplements you use. Allopurinol should not be used during pregnancy. It is unknown if this medication passes into breast milk.

Dosage

Allopurinol is available as a tablet and an oral suspension. It is typically taken once daily. The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may start you at a low dose and gradually increase your dose.

Warnings

Allopurinol may cause liver damage. You should have liver function tests before starting allopurinol and during treatment. You should also avoid drinking alcohol while taking allopurinol.

Allopurinol may also increase your risk of developing skin cancer. You should avoid prolonged exposure to sunlight and wear sunscreen and protective clothing while taking allopurinol.

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