PonstelWhat is Ponstel? Ponstel (mefenamic acid) is a nonsteroidal anti-inflammatory drug (NSAID). Mefenamic acid works by reducing hormones that cause inflammation and pain in the body. What is the most important information I should know about Ponstel? You should not use Ponstel if you are allergic to mefenamic acid, or if you have: history of heart disease, stroke, or blood clot; a history of stomach ulcers or bleeding; asthma; polycystic ovary syndrome; a bleeding or blood clotting disorder; if you are pregnant. How should I take Ponstel? Take Ponstel exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Ponstel can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). NSAIDs such as Ponstel may cause ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. The risk may be higher for people who take NSAIDs for a long time, are older in age, have poor health, or who drink three or more alcoholic drinks per day while taking Ponstel. Do not take Ponstel if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. Do not take Ponstel if you are breast-feeding a baby. What happens if I miss a dose? Since Ponstel is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Ponstel can be fatal. Overdose symptoms may include drowsiness, shallow breathing, slow heartbeat, extreme weakness, fainting, or coma. What should I avoid while taking Ponstel? Avoid drinking alcohol. It may increase your risk of stomach bleeding. Ponstel can make it harder for your body to absorb other medications you take. If you take other medications, take them at least 2 hours before or after you take Ponstel. Avoid taking aspirin or other NSAIDs while you are taking Ponstel. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Ponstel can make your skin more sensitive to sunlight and increase your risk of sunburn. Ponstel side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Ponstel and call your doctor at once if you have: shortness of breath (even with mild exertion), swelling, rapid weight gain; signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; heartburn, upset stomach, vomiting, loss of appetite, feeling full or bloated; swelling in your hands, ankles, or feet; drowsiness, confusion, mood changes, increased thirst, loss of appetite, or urinating less than usual or not at all; black, bloody, or tarry stools; coughing up blood or vomit that looks like coffee grounds; nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); flu-like symptoms (fever, chills, body aches); or easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin. Common Ponstel side effects may include: upset stomach, diarrhea; dizziness, headache; sleep problems (insomnia); or mild skin rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect Ponstel? Tell your doctor about all your current medicines and any you start or stop using, especially: a blood thinner such as warfarin (Coumadin, Jantoven); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (digitalis, Lanoxin); lithium (Eskalith, Lithobid); methotrexate (Rheumatrex, Trexall); a diuretic or "water pill"; steroids (prednisone and others); heart or blood pressure medication, such as amlodipine, diltiazem, nifedipine, verapamil; seizure medicine; or tuberculosis medicine. This list is not complete and many other drugs can interact with Ponstel. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you. Where can I get more information? Your pharmacist can provide more information about Ponstel.
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